Aryoseven is produced using recombinant BHK cells or newborn hamster kidney cells. These cells are maintained under cell bank regulations and stored in liquid nitrogen at a temperature of −185°C.
The active ingredient of Altebrel, known as etanercept, is prepared for final formulation after undergoing several stages of pre-purification and purification using chromatographic methods.
Zytux, with the generic name rituximab, is a chimeric (murine–human) monoclonal antibody directed against the CD20 antigen present on the surface of normal and malignant B lymphocytes, and is produced using recombinant DNA technology in Chinese hamster ovary (CHO) cells.
Aryotrust, or trastuzumab, is produced using CHO cells, or Chinese hamster ovary cells, as small biological factories for the production of this therapeutic antibody.
Stivant is used in the treatment of various cancers, including metastatic colorectal or anal cancer, advanced glioblastoma, non-small cell lung cancer, advanced or metastatic kidney cancer, ovarian cancer, fallopian tube cancer, primary peritoneal cancer, cervical cancer, and metastatic breast cancer.
Temziva can be used for the treatment of cytokine release syndrome (CRS) as the main cause of clinical deterioration in adult patients with confirmed COVID-19 infection (coronavirus disease).
Arylia contains the active ingredient denosumab, which has a protein structure. This protein (a monoclonal IgG2 antibody) specifically and selectively binds to the RANKL protein. RANKL is a protein that is essential for the formation, function, and survival of osteoclasts (bone-resorbing cells).
Vedolizumab is a monoclonal IgG1 antibody that binds to human α4β7 integrin and is produced using recombinant DNA technology in Chinese hamster ovary cells. Vedolizumab blocks a protein present on the surface of white blood cells that causes inflammation in ulcerative colitis and Crohn’s disease, thereby reducing the severity of inflammation.
AryoGen Pharmed produces numerous specialized pharmaceutical products that save the lives of many patients suffering from specific diseases such as cancer, hemophilia, and autoimmune diseases every day in Iran and some other parts of the world.
Artenix
Artenix contains the active ingredient denosumab, a protein structure. This protein (human IgG2 monoclonal antibody) specifically and targetedly binds to the RANKL protein.
Sinagene Pharmaceutical Group, relying on the technical knowledge and skills of its young specialists, intends to invest heavily each year to put a large number of products under its research and development projects, thereby providing greater foreign exchange savings. With the aim of providing better services in the field of health, Sinagene Pharmaceutical Group has been formed by 4 subsidiary companies centered on Sinagene Company as the parent company, which include the following companies:
We are always striving to open intellectual boundaries and export products.